Flat White Circles On Skin

Even less response

So yesterday, so it was my appointment with my neurologist at Nantes, I waited with great impatience. Well, a bit of disappointment for the answers I expected, he'll have to wait a bit ... He can not help me with the mystery of the failure of the toxin botulinum, it is "not sufficiently expert in this field" ...

Concerning a problem "second tier", but still important to me migraines. Beta-blockers were still pretty effective as maintenance treatment, since the number of crisis had diminished. But they are absolutely cons-indicated in combination with Mexitil, which treats myotonias. So we tried the last thing left to try: the tricyclic antidepressants. As this would be a shame to spoil the school, he prescribed the Cymbalta, which is one of the few to have no sedative effect. For

the channelopathy, nothing new, I just learned that genetic research that was launched was much largeque what I understood, with one hand ion channel analysis, and other analysis of genetic abnormalities responsible for progressive external ophthalmoplegia , in particular, mitochondrial citopathies .

To return to the botulinum toxin, the idea of a malformation of the neuromuscular junction is eliminated according to him, just as if this were the case, botulinum toxin would have been disastrous. We can not say she was ... He then told me to take appointment with Pr Pereon center rare neuromuscular disease, which is stalled on it. A little more waiting until June 30

Finally, do not stop there way visit to the optometrist on Monday in Toulouse.

Usi Mainboard Treiber

Mexitil green light cardiologist

A week after the resumption of Mexitil (just a reminder I had stopped after a few days because of gastrointestinal symptoms, to avoid any risk of arrhythmia hypokalemia), I find myself at home again the cardiologist to control everything. The

digestive problems returned from the 3rd day of treatment, but I waited firm foot to blow rice-banana-chocolate :-) Well we'll have to continue a diet adapted to this situation because Mexitil is intended for treatment on a long, sometimes very long term, it doesn encouraged him not to deal with other consequences Medoc side effects of initial treatment ...

Regarding heart rate, it is slow . After racing, my pulse was 50 beats per minute , which based on the Cardio is undoubtedly an effect of Mexitil. I-cons are listed all the humps heart, including beta-blockers, on pain of having to wear a pacemaker, which, again, would be a shame. The ECG also showed a arrhythmia (extra-systolic?) Which remains in tolerable. We will do a holter if I am still unwell or if I feel fibrillation. Finally

voltage side, it was 9 / 6. And there, mexiletine has nothing to do. J'épaississe just need a little. At the slightest blow as my "GI" in recent weeks, my muscle mass back, and it is not good for the tension, nor for my suspected channelopathy. So: eat salty liquorice and do sports! (The great sport that I am welcomes the idea ... ... ... to take the 30th degree).

So much for my little heart. I talked a little in passing the failure of botulinum toxin was the first time she had heard no immunological resistance to this toxin.
Next Tuesday, the neurologist appointment in Nantes. Deeply answers ...

Who Makes Driglo Nappies

resistance to botulinum toxin Botox Injection

4 days after my second botox injection, I'm back at the optometrist this morning, to the same conclusion as last time: nothing happens. Or almost.
Yet he "put the dose (more than 10 IU), yet it I have not passed in the late morning, and yet her other patients have reacted well, some very next day. So we can not accuse a technical problem.

So according to the ophthalmologist, the hypothesis of immunological resistance is very unlikely for several reasons:
- the existence of resistance due to antibodies neutralizing botulinum toxin has not been proven,
- the doses used in ophthalmology are far too small to trigger such a reaction,
- the appearance of antibodies can be done only after several repeated injections, and certainly not soon the first time
- I asked if it was possible that one day I have eaten food contaminated with botulinum toxin and this has triggered an immune response, response: "we must not exaggerate, and botulism usually one realizes, "
- again, my left eyelid started to fall slightly (ptosis), which means that the toxin has spread and has an effect on my lifter eyelid ...

remains to understand why my reaction to botox eyelid, not my ocular muscles, while it's still where the injection was made! The ophthalmologist
I explained that botulinum toxin blocks the transmission at the neuromuscular junction, it is likely that the spasms and nystagmus have a myogenic origin strictly , making them insensitive to the effect of the toxin . I would not have a disruption of the order, but a pure muscle spasticity associated with something a bit "chaotic" muscles, which gives the appearance of nystagmus. Nystagmus which incidentally is not synchronous on the 2 eyes (sometimes unilaterally, sometimes on a vertical and horizontal eye on the other ...). For now, we embark on an explanation of this type. The ophthalmologist will still apply their views to the 2 strabologues CHU Nantes.

Regarding the retina : I gave him the report of the ERG increased to Nantes and leaves evoke a problem on the cone of the left eye. He said that the protocol used was insufficient to conclude, therefore he speak to the clinic Sourdille Nantes to make a complete study: ERG with dark adaptation, EPI, EOG and visual field. Then it turns out there actually reaching the retina, we could possibly make connections, which might help in the diagnosis ...